The Effects of Tannin-Coated and High-Efficiency Zinc Replacing Conventional Zinc Oxide on Growth Performance in Weaned Piglets
Release date:
2025-08-01
| In recent years, tannins have emerged as a prominent and highly effective alternative to antibiotics in animal feed, earning widespread favor among manufacturers and gradually becoming a key product replacing zinc oxide. Adding specific doses of tannins to feed not only helps effectively control diarrhea in animals but also enhances the utilization of nutrients, boosts their stress resistance and immune system, and ultimately promotes growth. "Wei Chang Ning," "An Chang Fen M50," and "An Chang Fen M40" are tannin-based products developed by Guangdong Nan Kun Biotechnology Co., Ltd. These innovative formulations are crafted using high-quality tannin raw materials sourced from overseas, combined with cutting-edge encapsulation technology. This ensures that the tannins retain their palatability in feed while allowing for a controlled, gradual release in the later sections of the digestive tract—specifically targeting damaged areas of the intestine, thereby reducing diarrhea and improving overall animal performance. |
This experiment uses weaned piglets as the research subjects, and its objective is:
① Investigating the impact of replacing part of conventional zinc oxide in early-weaned piglets' diets with coated tannins on their growth performance.
② Investigate the effects of combining coated tannins with low-dose, highly effective zinc—used together to completely replace high-dose conventional zinc oxide—on the growth performance of late-weaned piglets in their diet.
③ Explore the application differences between two tannin products—Weichangning and Anchangfen M50—with identical effective doses but different coating types;
④ Investigating the effects of coating tannins (Anchangfen M40) combined with highly effective zinc (Haoke Zinc), used as a complete replacement for conventional zinc oxide, on the production performance of weaned piglets.
Materials and Methods
Experimental Design and Grouping
The trial selected 120 healthy, weaned piglets with an average body weight of 6.40 ± 0.1 kg and similar ages, randomly divided into 5 treatment groups. The experimental period lasted 34 days, divided into two distinct phases: a creep feed phase lasting 17 days, followed by a nursery feed phase also lasting 17 days.
Table 1: Experimental Design for Phase 1 (1–2 Weeks Post-Weaning, Creep Feeding Stage)
Group Category | Levels of addition in the basal diet |
Empty group | —— |
Control group | 2000 g/t conventional zinc oxide |
Trial Group 1 | 1000 g/t Wei Chang Ning + 1000 g/t conventional zinc oxide |
Trial Group 2 | 1000 g/t Anchangfen M50 + 1000 g/t conventional zinc oxide |
Trial Group 3 | 1800 g/t Anchangfen M40 + 200 g/t Hao Kai Zinc |
Table 2: Experimental Design for Phase 2 (3–4 Weeks After Weaning, Grower Feed Stage)
Group Category | Levels of addition in the basal diet |
Empty group | —— |
Control group | 2000 g/t conventional zinc oxide |
Trial Group 1 | 1200g/t Wei Chang Ning + 200 g/t easily soluble zinc |
Trial Group 2 | 1200 g/t Anchangfen M50 + 200 g/t Hao Kai Zinc |
Trial Group 3 | 500g/t Easy-to-Apply Zinc |
Note: Wei Chang Ning: Enteric-coated plant tannins, with an effective content of ≥50%;
Anchangfen M50: Slow-release coated plant tannins with an effective content of ≥50%;
Anchangfen M40: Slow-release coated plant tannins with an effective content of ≥40%;
Well-opened zinc: Nano zinc oxide, with an effective ZnO content of ≥70%.
Test location and time: The trial was conducted at the Guangdong Academy of Agricultural Sciences' experimental pig farm from August 30, 2023, to October 3, 2023, lasting a total of 34 days.
Experimental Diet
Table 3: Basal Diet for Phase 1 Trial
Ingredient Composition | Percentage % | Nutritional value | Content |
Corn | 29.00 | Digestible Energy (Kcal/kg) | 3335 |
Puffed corn | 34.00 | Crude Protein (%) | 19.37% |
Whey powder | 8.00 | Calcium (%) | 0.90% |
Fermented soybean meal | 10.00 | Available Phosphorus (%) | 0.58% |
46% Soybean Meal | 10.00 | Lysine (%) | 1.23% |
Fishmeal | 4.00 | Egg + Cystine (%) | 0.84% |
Mold inhibitor | 0.20 | Threonine (%) | 0.71% |
Lysine | 0.50 | Tryptophan (%) | 0.23% |
Methionine | 0.20 |
|
|
Premix | 4.00 |
|
|
Total | 99.90 |
|
Table 4: Basal Diet for Phase 2 Trial
Ingredient Composition | More than Example% | Nutritional value | Contains Quantity |
Corn | 68.50 | Digestible energy | 3382Kcal/kg |
46% Soybean Meal | 24.00 | Crude Protein (%) | 18.63% |
Fishmeal | 3.00 | Calcium (%) | 0.75% |
L-Lysine | 0.20 | Available Phosphorus (%) | 0.45% |
DL-Methionine | 0.10 | Lysine (%) | 1.14% |
Tryptophan | 0.01 | Egg + Cystine (%) | 0.74% |
Mold inhibitor | 0.20 | Threonine (%) | 0.68% |
Premix | 4.00 | Tryptophan (%) | 0.24% |
Total | 100.01 |
|
Test indicator measurement: Daily record the feed intake, number and weight of dead or culled pigs, and calculate the average daily gain, daily feed consumption, feed-to-meat ratio, as well as the mortality and diarrhea rates during each phase of the trial.
Results and Analysis
Analysis of the results from the first-phase trial
Table 5: Production Performance of Piglets in Each Group During the First Phase (1–2 Weeks Post-Weaning)
Group Category | Group 1 | Group 2 | Group 3 | Group 4 | Group 5 |
Add horizontal | —— | 2000g/t ZnO | 1000g/t Wei Chang Ning +1000 g/t ZnO | 1000 g/t Anchangfen M50 + 1000 g/t ZnO | 1800 g/t Anchangfen M40 +200g/t Easy-to-Apply Zinc |
Initial weight (kg) | 6.39 ± 0.41 | 6.39 ± 0.41 | 6.40 ± 0.41 | 6.41 ± 0.4 | 6.41 ± 0.41 |
Final weight (kg) | 10.33 ± 0.61b | 11.68 ± 0.65a | 11.67 ± 0.7a | 11.68 ± 0.58a | 11.04 ± 0.75 ab |
Total Weight Gain (kg) | 3.95 ± 0.21b | 5.28 ± 0.24a | 5.26 ± 0.37a | 5.28 ± 0.2a | 4.63 ± 0.35 ab |
Average daily weight gain (g) | 282 ± 15b | 377 ± 17a | 376 ± 26a | 377 ± 15 a | 331 ± 25ab |
Total Feed Intake (kg) | 54.77 ± 3.31b | 68.27 ± 2.74a | 65.5 ± 6.11 years | 66.47 ± 3.84a | 58.63 ± 5.05 ab |
Average daily feed intake (g) | 488.99 ± 29.55b | 609.52 ± 24.42a | 584.82 ± 54.53a | 593.45 ± 34.32a | 523.51 ± 5.12ab |
Feed-to-meat ratio | 1.73 ± 0.03a | 1.62 ± 0.04b | 1.55 ± 0.05b | 1.57 ± 0.06b | 1.58 ± 0.03b |
Diarrhea Rate (%) | 3.71% | 2.54% | 2.33% | 2.88% | 2.92% |
Diarrhea Index (Score) | 0.52 ± 0.05 years | 0.27 ± 0.03c | 0.27 ± 0.06c | 0.34 ± 0.04 bc | 0.35 ± 0.01 ab |
Note: In the same column, identical letter symbols indicate no significant difference (P > 0.05), while different lowercase letters denote a highly significant difference (P < 0.05). The same applies to the table below.
Results indicate that the nutritional programs in Groups 2, 3, and 4 exhibited equivalent efficacy in improving gut health (reducing diarrhea) and enhancing appetite (increasing feed intake) in piglets, with Group 5 performing slightly better. However, when it comes to feed efficiency—as measured by feed-to-meat ratio and piglet weight gain—while the high-dose zinc oxide group successfully prevented diarrhea, its feed-to-meat ratio was higher compared to the nutritional programs that replaced half of the zinc oxide (Groups 2 and 3). Although Group 5 showed lower feed intake and weight gain than Group 2, its feed-to-meat ratio was marginally better than the zinc oxide group, suggesting that the high dose of zinc oxide may impair the gut’s ability to efficiently absorb and convert dietary nutrients.
Analysis of Phase 2 Trial Results
Table 6: Production Performance of Piglets in Each Group During the Second Phase (3–4 Weeks After Weaning)
Group Category | Group 1 | Group 2 | Group 3 | Group 4 | Group 5 |
Add horizontal | —— | 2000g/t ZnO | 1200g/t Wei Chang Ning +200g/t Easy-to-Apply Zinc | 1200 g/t Anchangfen M50 +200g/t Easy-to-Apply Zinc | 500g/t Easy-to-Apply Zinc |
Initial weight (kg) | 10.33 ± 0.61b | 11.68 ± 0.65a | 11.67 ± 0.7a | 11.68 ± 0.58a | 11.04 ± 0.75 ab |
Final weight (kg) | 16.08 ± 0.99b | 18.52 ± 0.99a | 18.96 ± 1.07a | 19.04 ± 0.77a | 17.89 ± 0.98 ab |
Total Weight Gain (kg) | 5.74 ± 0.4b | 6.84 ± 0.35a | 7.29 ± 0.38a | 7.36 ± 0.22a | 6.85 ± 0.23a |
Average daily weight gain (g) | 410 ± 29b | 489 ± 25a | 521 ± 27a | 526 ± 15 a | 489 ± 16a |
Total Feed Intake (kg) | 89.23 ± 8.06b | 111.25 ± 1.99a | 108.75 ± 4.33a | 110.4 ± 1.76a | 98.85 ± 3.59 ab |
Average daily feed intake (g) | 796.73 ± 71.96a | 993.3 ± 17.74a | 970.98 ± 38.63a | 985.71 ± 15.74a | 882.59 ± 2.07 ab |
Feed-to-meat ratio | 1.94 ± 0.04b | 2.04 ± 0.09b | 1.87 ± 0.02ab | 1.88 ± 0.03 ab | 1.8 ± 0.01a |
Diarrhea Rate (%) | 0.60% | 0.19% | 0.11% | 0.19% | 0.15% |
Diarrhea Index (Score) | 0.083 ± 0.029 years | 0.015 ± 0.006b | 0.009 ± 0b | 0.03 ± 0.013b | 0.012 ± 0.003 b |
Results indicate that the nutritional programs in Groups 2, 3, 4, and 5 had equivalent effects on piglet growth performance. However, when evaluating feed efficiency—specifically through feed-to-gain ratios and piglet weight gain—we observed that while the high-dose zinc oxide (Group 2) did enhance feed intake in piglets, Groups 3, 4, and 5, which combined coated tannins with highly bioavailable zinc, demonstrated superior overall production outcomes, including better weight gain and improved feed conversion efficiency.
Analysis of trial results from all phases
Table 7: Production Performance of Piglets in Each Group During the Entire Trial Period (1–4 Weeks After Weaning)
Group Category | Group 1 | Group 2 | Group 3 | Group 4 | Group 5 |
Initial weight (kg) | 6.39 ± 0.41 | 6.39 ± 0.41 | 6.40 ± 0.41 | 6.41 ± 0.4 | 6.41 ± 0.41 |
Final weight (kg) | 16.08 ± 0.99b | 18.52 ± 0.99a | 18.96 ± 1.07a | 19.04 ± 0.77a | 17.89 ± 0.98 ab |
Total Weight Gain (kg) | 9.69 ± 0.61b | 12.13 ± 0.59a | 12.55 ± 0.7a | 12.64 ± 0.37a | 11.48 ± 0.58 ab |
Average daily weight gain (g) | 346 ± 22b | 433 ± 21a | 448 ± 25a | 451 ± 13a | 410 ± 21ab |
Total Feed Intake (kg) | 143.82 ± 11.39b | 179.48 ± 4.68a | 175.13 ± 9.84a | 176.87 ± 5.53a | 157.45 ± 8.62 ab |
Average daily feed intake (g) | 642.04 ± 50.86b | 801.26 ± 20.91a | 781.85 ± 43.91a | 789.58 ± 24.67a | 702.9 ± 38.48 ab |
Feed-to-meat ratio | 1.85 ± 0.04a | 1.86 ± 0.06 years | 1.74 ± 0.02b | 1.75 ± 0.01b | 1.71 ± 0.02b |
Diarrhea Rate (%) | 2.14% | 1.36% | 1.23% | 1.53% | 1.54% |
Diarrhea Index (Score) | 0.301 ± 0.012a | 0.141 ± 0.016 b | 0.141 ± 0.029b | 0.188 ± 0.022b | 0.183 ± 0.007 b |
Results indicate that the nutritional programs in Groups 2, 3, and 4 had equivalent effects on piglet growth performance. However, when it comes to feed efficiency—as reflected by feed-to-gain ratio and piglet weight gain—we observed that while the high dose of zinc oxide did encourage increased feed intake in piglets, the combination of coated tannins with highly bioavailable zinc delivered superior production outcomes in terms of both weight gain and feed conversion efficiency.
Conclusion
| After weaning piglets, initially use 1000 g/t of coated tannins (Weichangning, Anchangfen M50) combined with 1000 g/t of conventional zinc oxide. Later on, switch to 1200 g/t of coated tannins (Weichangning, Anchangfen M50) plus 200 g/t of highly effective zinc (Haoke Zinc), which can replace the previous 2000 g/t of conventional zinc oxide. This approach not only helps maintain performance but also further boosts weight gain, improves feed conversion ratio, and enhances overall production efficiency in weaned piglets. |
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